DCDC2 and NMU

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DCDC2	NMU
Description		doublecortin domain containing 2	neuromedin U
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Microtubule Cilium Axoneme Microtubule Cytoskeleton Centriolar Satellite Kinocilium Mitotic Spindle	Extracellular Region Terminal Bouton
	Molecular Function	Protein Binding Kinesin Binding	Signaling Receptor Binding Protein Binding Type 1 Neuromedin U Receptor Binding Type 2 Neuromedin U Receptor Binding Neuromedin U Receptor Binding
	Biological Process	Neuron Migration Cellular Defense Response Sensory Perception Of Sound Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly	Temperature Homeostasis Gastric Acid Secretion Positive Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Photoperiodism Positive Regulation Of Heart Rate Sensory Perception Of Pain Positive Regulation Of Heat Generation Eating Behavior Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Synaptic Transmission Negative Regulation Of Gastric Acid Secretion Energy Homeostasis Negative Regulation Of Gastric Emptying Positive Regulation Of Stomach Fundus Smooth Muscle Contraction Positive Regulation Of Prolactin Secretion Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Regulation Of Grooming Behavior
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Estimated glomerular filtration rate ( 31152163 31015462) General cognitive ability ( 29844566) Information processing speed ( 21130836) Uric acid levels ( 21294900)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 32277301 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432	16 interacting genes: CYSRT1 DCDC2 KRT34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-6 KRTAP12-3 KRTAP17-1 KRTAP5-9 NBPF19 NMUR1 NMUR2 NOTCH2NLA SNTA1 TNS2
Entrez ID		51473	10874
HPRD ID		09308	05485
Ensembl ID		ENSG00000146038	ENSG00000109255
Uniprot IDs		Q9UHG0	A0A0B4J202 A0A250SH36 E9PDJ7 P48645 Q86WB6
PDB IDs		2DNF
Enriched GO Terms of Interacting Partners?
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