NMU and NMUR2

Number of citations of the paper that reports this interaction (PubMedID 10894543)
80

Data Source:
HPRD (in vivo, in vitro)

		NMU	NMUR2
Description		neuromedin U	neuromedin U receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Terminal Bouton	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Type 1 Neuromedin U Receptor Binding Type 2 Neuromedin U Receptor Binding Neuromedin U Receptor Binding	Neuromedin U Receptor Activity G Protein-coupled Receptor Activity Intracellular Calcium Activated Chloride Channel Activity Protein Binding GTP Binding Neuropeptide Receptor Activity Neuromedin U Binding
	Biological Process	Temperature Homeostasis Gastric Acid Secretion Positive Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Photoperiodism Positive Regulation Of Heart Rate Sensory Perception Of Pain Positive Regulation Of Heat Generation Eating Behavior Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Synaptic Transmission Negative Regulation Of Gastric Acid Secretion Energy Homeostasis Negative Regulation Of Gastric Emptying Positive Regulation Of Stomach Fundus Smooth Muscle Contraction Positive Regulation Of Prolactin Secretion Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Regulation Of Grooming Behavior	Reduction Of Food Intake In Response To Dietary Excess Calcium Ion Transport Regulation Of Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Central Nervous System Development Grooming Behavior Feeding Behavior Inorganic Anion Transport Calcium-mediated Signaling Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Inositol Phosphate-mediated Signaling Response To Pain Arachidonic Acid Secretion Regulation Of Sensory Perception Of Pain
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 32277301 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Ability to confide in someone ( 29970889) Adult body size ( 32376654) Bipolar disorder ( 33169155) Bipolar disorder and schizophrenia ( 22688191) Body size at age 10 ( 32376654) Caffeine consumption from tea ( 33287642) Chronotype ( 30696823) Feeling lonely ( 29500382) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Manganese levels ( 26025379) Metabolite levels ( 23823483) Morning person ( 30696823) Number of sexual partners ( 30643258) Optic nerve measurement (cup area) ( 20395239) Periodontitis (PAL4Q3) ( 24024966) Schizophrenia ( 28991256) Sedentary behaviour duration ( 30531941) Subjective well-being ( 27089181)
Interacting Genes		16 interacting genes: CYSRT1 DCDC2 KRT34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-6 KRTAP12-3 KRTAP17-1 KRTAP5-9 NBPF19 NMUR1 NMUR2 NOTCH2NLA SNTA1 TNS2	6 interacting genes: ADAMTSL4 KRTAP13-1 NMU NOTCH2NLA TCF4 TRAF2
Entrez ID		10874	56923
HPRD ID		05485	12003
Ensembl ID		ENSG00000109255	ENSG00000132911
Uniprot IDs		A0A0B4J202 A0A250SH36 E9PDJ7 P48645 Q86WB6	Q9GZQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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