FAM8A1 and GMPR

		FAM8A1	GMPR
Description		family with sequence similarity 8 member A1	guanosine monophosphate reductase
Image		No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Integral Component Of Membrane	Cytosol GMP Reductase Complex
	Molecular Function	Protein Binding	GMP Reductase Activity Metal Ion Binding
	Biological Process	Ubiquitin-dependent ERAD Pathway	Purine Nucleobase Metabolic Process Purine Nucleotide Metabolic Process Response To Cold
Pathways			Purine salvage
Drugs			Guanosine-5'-Monophosphate
Diseases
GWAS		Idiopathic intracranial hypertension ( 29608535)	Blood metabolite levels ( 24816252) Gambling ( 22780124) General cognitive ability ( 29844566) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 20864672) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean spheric corpuscular volume ( 32888494) QT interval ( 24952745 29874175) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Response to statins (LDL cholesterol change) ( 22331829) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		5 interacting genes: ATP13A2 CD83 GMPR H4C13 SLC17A4	3 interacting genes: CD83 FAM8A1 RIPK1
Entrez ID		51439	2766
HPRD ID		13316	00754
Ensembl ID		ENSG00000137414	ENSG00000137198
Uniprot IDs		A0A024R006 Q9UBU6	P36959
PDB IDs			2BLE 2BWG
Enriched GO Terms of Interacting Partners?
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