GMPR and FAM8A1

		GMPR	FAM8A1
Description		guanosine monophosphate reductase	family with sequence similarity 8 member A1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol GMP Reductase Complex	Hrd1p Ubiquitin Ligase Complex Integral Component Of Membrane
	Molecular Function	GMP Reductase Activity Metal Ion Binding	Protein Binding
	Biological Process	Purine Nucleobase Metabolic Process Purine Nucleotide Metabolic Process Response To Cold	Ubiquitin-dependent ERAD Pathway
Pathways		Purine salvage
Drugs		Guanosine-5'-Monophosphate
Diseases
GWAS		Blood metabolite levels ( 24816252) Gambling ( 22780124) General cognitive ability ( 29844566) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 20864672) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean spheric corpuscular volume ( 32888494) QT interval ( 24952745 29874175) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Response to statins (LDL cholesterol change) ( 22331829) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Idiopathic intracranial hypertension ( 29608535)
Interacting Genes		3 interacting genes: CD83 FAM8A1 RIPK1	5 interacting genes: ATP13A2 CD83 GMPR H4C13 SLC17A4
Entrez ID		2766	51439
HPRD ID		00754	13316
Ensembl ID		ENSG00000137198	ENSG00000137414
Uniprot IDs		P36959	A0A024R006 Q9UBU6
PDB IDs		2BLE 2BWG
Enriched GO Terms of Interacting Partners?
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