DDX41 and TRIM26

Number of citations of the paper that reports this interaction (PubMedID 33373584)
7

Data Source:
BioGRID (pull down)

		DDX41	TRIM26
Description		DEAD-box helicase 41	tripartite motif containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol Membrane Catalytic Step 2 Spliceosome	Cellular_component Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity Metal Ion Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process Cell Population Proliferation Cell Differentiation	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN	Interferon gamma signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Hematocrit ( 32888494) LDL cholesterol levels ( 32203549) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 21926974 22883433 30285260) Squamous cell lung carcinoma ( 28604730) Triglyceride levels ( 32203549) Waist-hip index ( 34021172)
Interacting Genes		10 interacting genes: AIDA CEP70 CHAF1A KLC2 NKAPL OGT SIAH1 TRIM26 TRIM41 TUBG1	28 interacting genes: BEND7 BIVM DDX41 EPN2 EPN3 INCA1 IRF3 LMNA MACROH2A1 MAGEA6 MIR138-2 MIR18B MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 SUMO2 THAP1 TLE5 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5
Entrez ID		51428	7726
HPRD ID		10490	02901
Ensembl ID		ENSG00000183258	ENSG00000234127
Uniprot IDs		B3KRK2 Q9UJV9	A0A024RCP3 Q12899
PDB IDs		2P6N 5GVR 5GVS 5H1Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?