DDX41 and KLC2

Number of citations of the paper that reports this interaction (PubMedID 30217970)
5

Data Source:
BioGRID (two hybrid)

		DDX41	KLC2
Description		DEAD-box helicase 41	kinesin light chain 2
Image
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol Membrane Catalytic Step 2 Spliceosome	Nucleoplasm Mitochondrion Lysosomal Membrane Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity Metal Ion Binding	Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process Cell Population Proliferation Cell Differentiation	Lysosome Localization
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: AIDA CEP70 CHAF1A KLC2 NKAPL OGT SIAH1 TRIM26 TRIM41 TUBG1	18 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 DYNC1I1 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PACS1 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ
Entrez ID		51428	64837
HPRD ID		10490	13917
Ensembl ID		ENSG00000183258	ENSG00000174996
Uniprot IDs		B3KRK2 Q9UJV9	Q9H0B6
PDB IDs		2P6N 5GVR 5GVS 5H1Y	3CEQ 3EDT
Enriched GO Terms of Interacting Partners?
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