BIN2 and FAM3B

		BIN2	FAM3B
Description		bridging integrator 2	FAM3 metabolism regulating signaling molecule B
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Podosome Extracellular Region Plasma Membrane Cell Cortex Cell Junction Secretory Granule Lumen Cell Projection Ficolin-1-rich Granule Lumen	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Protein Binding Phospholipid Binding	Cytokine Activity Protein Binding
	Biological Process	Phagocytosis, Engulfment Cell Chemotaxis Podosome Assembly Plasma Membrane Tubulation	Apoptotic Process Signal Transduction Insulin Secretion Glucose Homeostasis
Pathways		Neutrophil degranulation Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
Drugs
Diseases
GWAS		Aging (time to death) ( 21782286) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)	Blood protein levels ( 30072576 29875488) Elevated serum carcinoembryonic antigen levels ( 24941225) Glycemic traits (pregnancy) ( 23903356) Tumor biomarkers ( 23300138)
Interacting Genes		5 interacting genes: APPBP2 FAM3B POT1 TERF1 TINF2	8 interacting genes: APP BIN2 COL6A1 FCGR2A FUT3 H2BS1 KCNAB2 MAP3K7CL
Entrez ID		51411	54097
HPRD ID		05805	10552
Ensembl ID		ENSG00000110934	ENSG00000183844
Uniprot IDs		Q9UBW5	P58499
PDB IDs		4AVM 4I1Q
Enriched GO Terms of Interacting Partners?
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