FAM3B and FUT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM3B	FUT3
Description		FAM3 metabolism regulating signaling molecule B	fucosyltransferase 3 (Lewis blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome	Golgi Membrane Membrane Integral Component Of Membrane Golgi Cisterna Membrane Extracellular Exosome
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Fucosyltransferase Activity 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase Activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Activity Alpha-(1->3)-fucosyltransferase Activity
	Biological Process	Apoptotic Process Signal Transduction Insulin Secretion Glucose Homeostasis	Protein Glycosylation Ceramide Metabolic Process Oligosaccharide Metabolic Process Oligosaccharide Biosynthetic Process Cell-cell Recognition Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Migration Fucosylation Regulation Of Cell Population Proliferation Macromolecule Glycosylation
Pathways			Lewis blood group biosynthesis Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Elevated serum carcinoembryonic antigen levels ( 24941225) Glycemic traits (pregnancy) ( 23903356) Tumor biomarkers ( 23300138)	Blood protein levels ( 30072576 29875488 28240269) Elevated serum carcinoembryonic antigen levels ( 24941225) N-glycan levels ( 21908519 21203500) Serum alkaline phosphatase levels ( 33547301) Serum cancer antigen 19.9 levels ( 31666285) Vitamin B12 levels ( 28334792)
Interacting Genes		8 interacting genes: APP BIN2 COL6A1 FCGR2A FUT3 H2BS1 KCNAB2 MAP3K7CL	6 interacting genes: AKAP6 C3orf52 FAM3B SEC22A SLC41A2 TRARG1
Entrez ID		54097	2525
HPRD ID		10552	00196
Ensembl ID		ENSG00000183844	ENSG00000171124
Uniprot IDs		P58499	A8K737 P21217
PDB IDs
Enriched GO Terms of Interacting Partners?
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