PCSK5 and SHFL

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

PCSK5

SHFL

Description proprotein convertase subtilisin/kexin type 5 shiftless antiviral inhibitor of ribosomal frameshifting
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease progression score ( 29860282)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • Ankylosing spondylitis ( 30946743)
  • Apolipoprotein B levels ( 32203549)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body shape index ( 34021172)
  • Diverticular disease ( 30177863)
  • Glucocorticoid-induced osteonecrosis ( 26265699)
  • Glucose homeostasis traits ( 25524916)
  • Height ( 28552196 20881960 25282103 23563607 31562340)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hypotension and cognitive impairment ( 31362389)
  • Inflammatory bowel disease ( 27569725)
  • Intraocular pressure ( 29785010 31959993 30054594)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Lead levels ( 26025379)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Male fertility ( 22633400)
  • Metabolite levels (5-HIAA) ( 23319000)
  • Pursuit maintenance gain ( 29064472)
  • Response to fenofibrate (adiponectin levels) ( 23149075)
  • Schizophrenia, bipolar disorder or major depressive disorder ( 34099189)
  • Systemic sclerosis ( 30247649)
  • Takayasu arteritis ( 25604533)
  • Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
  • Vascular brain injury ( 25188341)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412)
  • Waist-hip index ( 34021172)
  • Weight ( 34074324)
Interacting Genes 72 interacting genes: ADAMTSL4 AMH APPBP2 ATN1 C17orf50 C22orf39 CACNA1A CCDC33 CLIC1 CREB5 CYSRT1 DBF4B DEK DOCK2 FAM86C1P FARS2 FRS3 GLRX3 GUCD1 HOXA1 HOXB9 INCA1 ITGA6 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP13-3 KRTAP19-2 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-9 LCE1D LCE1F LCE2C LCE3C LCE3D MDFI MEOX2 NBPF19 NOTCH2NLA NR1D2 NR4A3 NUFIP2 OTX1 PCSK6 PLSCR4 PMCH POU4F2 PTPRM REN SH3GLB1 SHFL SMCP SPRY1 SSC4D STK16 TEKT4 TLE5 TRAF4 TRIB3 TRIM42 TRIP13 USP54 VGLL3 ZNF547 ZNF655 ZNF837 67 interacting genes: ADAMTSL4 CADPS CCDC136 CCNDBP1 CYSRT1 DRICH1 DTNBP1 DVL3 ECSIT FBXL12 FHL5 HSF2BP IKZF1 INCA1 KLF15 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 LNX1 LURAP1 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NBPF19 NOTCH2NLA PCSK5 PDE4DIP PICK1 PPP2R5A SPRY2 SSX2IP TCF4 TENM4 TERF1 TLE5 TNS2 TRAF1 TRIB3 TRIM42 TRIM55 TRIM63 VWC2 ZNF835
Entrez ID 5125 55337
HPRD ID 08985 07747
Ensembl ID ENSG00000099139 ENSG00000130813
Uniprot IDs Q92824 Q9NUL5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?