ABI3 and SUFU

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

ABI3

SUFU

Description ABI family member 3 SUFU negative regulator of hedgehog signaling
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 28714976)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Asthma ( 31619474)
  • Family history of Alzheimer's disease ( 30617256)
  • Prostate cancer ( 23535732)
  • Refractive error ( 32231278)
  • Adult body size ( 32376654)
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergy ( 27182965)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Body shape index ( 34021172)
  • Brain morphology (MOSTest) ( 32665545)
  • Creatinine levels ( 29403010)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Eosinophil counts ( 32888494)
  • Estimated glomerular filtration rate ( 30604766)
  • Glomerular filtration rate ( 29403010)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Nickel levels ( 26025379)
  • Optic disc size ( 31809533)
  • Platelet count ( 32888494)
  • Prostate cancer ( 23535732)
  • Refractive error ( 32231278)
  • Sum eosinophil basophil counts ( 27863252)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • White blood cell count ( 29403010)
Interacting Genes 77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1 51 interacting genes: ABI3 AKR1C1 BFSP2 BTRC CRTC2 CRX DISC1 EDA2R FBXL17 FXR1 GLI1 GLI2 GLI3 GLIS3 HDX HMGA1 HNRNPA1 ITCH KRT27 KRT75 L3MBTL3 LAMTOR3 LCA5 LGALS3 LZTS1 MAGEL2 MEOX2 MID1IP1 NCOA3 PEX26 PIAS1 QPRT RBPJ RCN3 RNF19A SAP18 SETDB1 SH3RF1 SLC41A3 STK36 STX19 TLE5 ZIC1 ZNF114 ZNF219 ZNF263 ZNF330 ZNF446 ZNF763 ZNF764 ZSCAN18
Entrez ID 51225 51684
HPRD ID 05900 06124
Ensembl ID ENSG00000108798 ENSG00000107882
Uniprot IDs Q9P2A4 A0A223LX15 Q9UMX1
PDB IDs 1M1L 4BL8 4BL9 4BLA 4BLB 4BLD 4KM8 4KM9 4KMD 4KMH
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?