CRBN and SALL3

Number of citations of the paper that reports this interaction (PubMedID 30385546)
64

Data Source:
BioGRID (pull down)

		CRBN	SALL3
Description		cereblon	spalt like transcription factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	Protein Binding Transmembrane Transporter Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein-containing Complex Assembly Locomotory Exploration Behavior Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Large Conductance Calcium-activated Potassium Channel Activity	Regulation Of Transcription By RNA Polymerase II
Pathways		Potential therapeutics for SARS
Drugs		Lenalidomide Thalidomide Pomalidomide
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Immune response to smallpox vaccine (IL-6) ( 22542470) Knee osteoarthritis ( 27696742) Malaria ( 31844061) Restless legs syndrome ( 29029846) White blood cell count (basophil) ( 29403010 27863252) White matter integrity ( 23218918)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Attention function in attention deficit hyperactive disorder ( 26174813) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Metabolite levels ( 23823483) Prostate cancer ( 23535732) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Rheumatoid arthritis ( 18668548) Smoking initiation (ever regular vs never regular) ( 31089300) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		38 interacting genes: APPL2 BCL6 BCL6B BSG CSNK1A1 CUL4B CYP19A1 EGR1 EGR4 GLUL GRB2 GSPT1 GZF1 HIC1 HIC2 IKZF3 KDM1A KPNB1 MISP OSR1 OSR2 PAK5 PIK3R3 PRKAG1 RBPMS RBX1 SALL1 SALL3 SALL4 SLC16A1 SQSTM1 SUV39H1 TP53 UBE2D1 WIZ ZBTB7A ZBTB7B ZFP91	1 interacting genes: CRBN
Entrez ID		51185	27164
HPRD ID		16750	05467
Ensembl ID		ENSG00000113851	ENSG00000256463
Uniprot IDs		Q96SW2	A0A384MEH2 A9JR48 Q9BXA9
PDB IDs		4M91 4TZ4 5FQD 5HXB 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6H0F 6H0G 6UML 6XK9 7BQU 7BQV
Enriched GO Terms of Interacting Partners?
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