HSD17B11 and HTATIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSD17B11	HTATIP2
Description		hydroxysteroid 17-beta dehydrogenase 11	HIV-1 Tat interactive protein 2
Image
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Nucleus Nuclear Envelope Cytoplasm Cytosol Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity	Transcription Coactivator Activity Protein Serine/threonine Kinase Activity Protein Binding Oxidoreductase Activity
	Biological Process	Estrogen Biosynthetic Process Androgen Catabolic Process	Angiogenesis Regulation Of Transcription By RNA Polymerase II Apoptotic Process Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Import Into Nucleus
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone	Polyethylene glycol 400
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)	Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		54 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VEZT YIPF6	25 interacting genes: ABHD4 ACSL4 AQP6 ASF1A EHHADH ETS1 FAM209A FITM2 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 TMEM115 TMX2
Entrez ID		51170	10553
HPRD ID		10881	09288
Ensembl ID		ENSG00000198189	ENSG00000109854
Uniprot IDs		Q8NBQ5	Q9BUP3
PDB IDs		1YB1	2BKA
Enriched GO Terms of Interacting Partners?
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