EGFL7 and HEXIM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EGFL7	HEXIM2
Description		EGF like domain multiple 7	HEXIM P-TEFb complex subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Collagen-containing Extracellular Matrix	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Signaling Receptor Binding Calcium Ion Binding Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding
	Biological Process	Angiogenesis Blood Vessel Development Vasculogenesis Positive Regulation Of Endothelial Cell Proliferation Cell Adhesion Negative Regulation Of Notch Signaling Pathway Anatomical Structure Development	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Lean body mass ( 28552196) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Triiodothyronine levels and thyroxine levels ( 30843173)	Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)
Interacting Genes		17 interacting genes: FXR1 FXR2 GFI1B GNE HEXIM2 HGS HOXA1 HSD3B7 MID2 NOTCH1 NOTCH2 NOTCH3 NOTCH4 NUFIP2 RASSF10 SMARCD1 SPAG8	49 interacting genes: ADAMTSL4 AHCYL1 AP2M1 CACNB2 CCDC33 CCNT1 CDK9 CFP CTIF DBF4B EGFL7 FAM161A GAS8 GATA1 HEXIM1 HOXA1 HSF2BP IHO1 KPNA3 KPRP KRTAP13-3 LNX1 MEOX2 PICK1 PIM1 PIN1 PRDM14 PSMA1 RNPS1 SAXO1 SDCBP SPRED1 SPRY1 SPRY2 TADA3 TCF12 TERF1 TERF2 TLE5 TNFAIP1 TRIM14 YPEL3 ZNF250 ZNF426 ZNF500 ZNF558 ZNF655 ZNF699 ZNF789
Entrez ID		51162	124790
HPRD ID		16351	08129
Ensembl ID		ENSG00000172889	ENSG00000168517
Uniprot IDs		A0A024R8F5 Q9UHF1	Q96MH2
PDB IDs
Enriched GO Terms of Interacting Partners?
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