HEXIM2 and DBF4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HEXIM2	DBF4B
Description		HEXIM P-TEFb complex subunit 2	DBF4 zinc finger B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Chromatin Nucleus Nucleoplasm Cytoplasm Dbf4-dependent Protein Kinase Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated	Cell Cycle Positive Regulation Of Cell Population Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Cell Cycle Phase Transition
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		49 interacting genes: ADAMTSL4 AHCYL1 AP2M1 CACNB2 CCDC33 CCNT1 CDK9 CFP CTIF DBF4B EGFL7 FAM161A GAS8 GATA1 HEXIM1 HOXA1 HSF2BP IHO1 KPNA3 KPRP KRTAP13-3 LNX1 MEOX2 PICK1 PIM1 PIN1 PRDM14 PSMA1 RNPS1 SAXO1 SDCBP SPRED1 SPRY1 SPRY2 TADA3 TCF12 TERF1 TERF2 TLE5 TNFAIP1 TRIM14 YPEL3 ZNF250 ZNF426 ZNF500 ZNF558 ZNF655 ZNF699 ZNF789	17 interacting genes: CDC7 CYSRT1 GEM HEXIM2 HOXA1 KDM1A KRTAP4-12 LMO2 LRRK2 MDFI PCSK5 ROPN1 SGF29 SRPK2 SUV39H1 TRIM27 ZNF655
Entrez ID		124790	80174
HPRD ID		08129	16840
Ensembl ID		ENSG00000168517	ENSG00000161692
Uniprot IDs		Q96MH2	Q8NFT6
PDB IDs
Enriched GO Terms of Interacting Partners?
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