IER3IP1 and TRHR

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IER3IP1	TRHR
Description		immediate early response 3 interacting protein 1	thyrotropin releasing hormone receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Thyrotropin-releasing Hormone Receptor Activity Protein Binding
	Biological Process	Positive Regulation Of Extracellular Matrix Constituent Secretion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Brain Development Protein Transport Organ Growth Positive Regulation Of Protein Secretion Regulation Of Fibroblast Apoptotic Process	G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Protirelin
Diseases
GWAS		Fruit consumption ( 32066663)	Body mass (lean) ( 19268274) Daytime sleep phenotypes ( 27126917) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969)
Interacting Genes		43 interacting genes: AIG1 C19orf18 CDIPT CERS2 CERS4 CSNK2B CST1 DPM3 EBP ELOVL4 ERMP1 FAM210B FCER1G GJB1 GOSR2 GPR42 HERPUD2 JAGN1 KCNA1 MOSPD3 PEX12 PIGP PLP1 POMK RGS2 SCN3B SLC30A4 TK1 TM4SF18 TMEM128 TMEM14A TMEM14B TMEM167A TMEM237 TMEM258 TMEM80 TMEM86B TMPPE TMX2 TRHR UBQLN1 YIPF4 ZFYVE27	19 interacting genes: ARRB1 C1QL4 COMT EFNA5 FAM241B FXYD6-FXYD2 GJB2 IER3IP1 NIPAL4 PEDS1-UBE2V1 SLC39A2 SLC39A9 SLC41A1 TMEFF2 TMEM218 TMEM239 TRH UBE2J1 YIPF6
Entrez ID		51124	7201
HPRD ID		13727	11767
Ensembl ID		ENSG00000134049	ENSG00000174417
Uniprot IDs		Q9Y5U9	P34981
PDB IDs
Enriched GO Terms of Interacting Partners?
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