DERA and HSF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DERA	HSF2
Description		deoxyribose-phosphate aldolase	heat shock transcription factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Deoxyribose-phosphate Aldolase Activity Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Pentose-phosphate Shunt Deoxyribonucleotide Catabolic Process Carbohydrate Catabolic Process Deoxyribonucleoside Catabolic Process Deoxyribose Phosphate Catabolic Process	Regulation Of Transcription By RNA Polymerase II Spermatogenesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Neutrophil degranulation Pentose phosphate pathway
Drugs
Diseases
GWAS		Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Bone mineral density (hip) and age at menarche ( 26312577) Chronotype ( 30696823) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)	Atrial fibrillation ( 28416822 30061737 29892015) Disease progression in age-related macular degeneration ( 29346644) Lymphocyte counts ( 32888494 27863252) Optic cup area ( 25631615 31798171 28073927) Optic disc size ( 31809533) Pulse pressure ( 30224653 27841878) Red blood cell count ( 32888494) Subcutaneous adipose tissue ( 26480920) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Vertical cup-disc ratio ( 31798171 25241763) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Word reading ( 30741946)
Interacting Genes		3 interacting genes: ALDH16A1 CIT HSF2	19 interacting genes: CDC20 CDC27 CEP76 CUL3 DERA HSF1 HSF2BP MTUS2 NCAPG NUP62 PCGF2 PICK1 PPP2R1A SUMO2 SUMO3 TPM3 TRIM54 UBE2I WDR5
Entrez ID		51071	3298
HPRD ID		13138	00779
Ensembl ID		ENSG00000023697	ENSG00000025156
Uniprot IDs		E9PPM8 Q9Y315	Q03933 Q9BS48
PDB IDs			5D8K 5D8L 5HDK
Enriched GO Terms of Interacting Partners?
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