HSF2 and DERA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSF2	DERA
Description		heat shock transcription factor 2	deoxyribose-phosphate aldolase
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Extracellular Region Nucleoplasm Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	Deoxyribose-phosphate Aldolase Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Spermatogenesis Positive Regulation Of Transcription By RNA Polymerase II	Pentose-phosphate Shunt Deoxyribonucleotide Catabolic Process Carbohydrate Catabolic Process Deoxyribonucleoside Catabolic Process Deoxyribose Phosphate Catabolic Process
Pathways			Neutrophil degranulation Pentose phosphate pathway
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416822 30061737 29892015) Disease progression in age-related macular degeneration ( 29346644) Lymphocyte counts ( 32888494 27863252) Optic cup area ( 25631615 31798171 28073927) Optic disc size ( 31809533) Pulse pressure ( 30224653 27841878) Red blood cell count ( 32888494) Subcutaneous adipose tissue ( 26480920) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Vertical cup-disc ratio ( 31798171 25241763) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Word reading ( 30741946)	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Bone mineral density (hip) and age at menarche ( 26312577) Chronotype ( 30696823) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
Interacting Genes		19 interacting genes: CDC20 CDC27 CEP76 CUL3 DERA HSF1 HSF2BP MTUS2 NCAPG NUP62 PCGF2 PICK1 PPP2R1A SUMO2 SUMO3 TPM3 TRIM54 UBE2I WDR5	3 interacting genes: ALDH16A1 CIT HSF2
Entrez ID		3298	51071
HPRD ID		00779	13138
Ensembl ID		ENSG00000025156	ENSG00000023697
Uniprot IDs		Q03933 Q9BS48	E9PPM8 Q9Y315
PDB IDs		5D8K 5D8L 5HDK
Enriched GO Terms of Interacting Partners?
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