GLRX2 and ELF5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GLRX2	ELF5
Description		glutaredoxin 2	E74 like ETS transcription factor 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body Intracellular Membrane-bounded Organelle	Chromatin Nucleus
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Arsenate Reductase (glutaredoxin) Activity Electron Transfer Activity Glutathione Disulfide Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding Glutathione Oxidoreductase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Glutathione Metabolic Process Apoptotic Process Aging Response To Temperature Stimulus Regulation Of Signal Transduction Response To Organic Substance Electron Transport Chain Cell Differentiation DNA Protection Response To Hydrogen Peroxide Cell Redox Homeostasis Response To Redox State Cellular Response To Superoxide	Regulation Of Transcription By RNA Polymerase II Cell Differentiation
Pathways
Drugs		Glutathione
Diseases
GWAS		Blood protein levels ( 29875488)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: DCXR DENND1B ELF5 FBXO7 NUTF2 TXNRD1	10 interacting genes: ACTR2 FRZB GLRX2 NFE2 NFE2L2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4
Entrez ID		51022	2001
HPRD ID		12112	05525
Ensembl ID		ENSG00000023572	ENSG00000135374
Uniprot IDs		Q9NS18	A0A087X1W9 A8K443 Q9UKW6
PDB IDs		2CQ9 2FLS 2HT9	1WWX
Enriched GO Terms of Interacting Partners?
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