TPRKB and TP53RK

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		TPRKB	TP53RK
Description		TP53RK binding protein	TP53 regulating kinase
Image
GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Cytoplasm Cytosol	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding	P53 Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Hydrolase Activity Protein Serine Kinase Activity
	Biological Process	Telomere Maintenance Via Recombination TRNA Threonylcarbamoyladenosine Modification	Protein Phosphorylation TRNA Processing TRNA Threonylcarbamoyladenosine Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator
Pathways		tRNA modification in the nucleus and cytosol	tRNA modification in the nucleus and cytosol Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Creatinine levels ( 20383145) Estimated glomerular filtration rate in diabetes ( 31451708) Metabolite levels ( 21931564) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 33031748 23093944)	Dimensional psychopathology (Arousal) ( 29496196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: TP53RK TRIM27	12 interacting genes: CALCOCO2 CHN2 CLK1 DCTN1 GORASP2 LRRC2 MDM2 MTUS2 OSGEP SYNE1 TP53 TPRKB
Entrez ID		51002	112858
HPRD ID		12277	12276
Ensembl ID		ENSG00000144034	ENSG00000172315
Uniprot IDs		Q9Y3C4	Q96S44
PDB IDs		3ENP 6WQX	6WQX
Enriched GO Terms of Interacting Partners?
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