TP53RK and SYNE1

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		TP53RK	SYNE1
Description		TP53 regulating kinase	spectrin repeat containing nuclear envelope protein 1
Image
GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm	P-body Nucleus Nuclear Envelope Nuclear Outer Membrane Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytoskeleton Integral Component Of Membrane Sarcomere Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Postsynaptic Membrane
	Molecular Function	P53 Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Hydrolase Activity Protein Serine Kinase Activity	RNA Binding Actin Binding Protein Binding Lamin Binding Enzyme Binding Protein Homodimerization Activity Actin Filament Binding Cytoskeleton-nuclear Membrane Anchor Activity
	Biological Process	Protein Phosphorylation TRNA Processing TRNA Threonylcarbamoyladenosine Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator	Nucleus Organization Golgi Organization Spermatogenesis Muscle Cell Differentiation Nuclear Matrix Anchoring At Nuclear Membrane
Pathways		tRNA modification in the nucleus and cytosol Regulation of TP53 Activity through Phosphorylation	Meiotic synapsis
Drugs
Diseases
GWAS		Dimensional psychopathology (Arousal) ( 29496196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 28115744 21926972 31043756 28072414 20351715 21738484) Bipolar disorder or major depressive disorder ( 20351715) Bipolar I disorder ( 31043756) Body mass index ( 26426971) Endometriosis ( 28537267) Heel bone mineral density ( 30598549 28869591) Hip circumference adjusted for BMI ( 34021172) Post bronchodilator FEV1 ( 26634245) Tonometry ( 17903302) Uterine fibroids ( 31249589 30194396 31649266)
Interacting Genes		12 interacting genes: CALCOCO2 CHN2 CLK1 DCTN1 GORASP2 LRRC2 MDM2 MTUS2 OSGEP SYNE1 TP53 TPRKB	32 interacting genes: ACTC1 AKAP12 APC BDKRB2 CAPN1 CDC42 CDC5L CEP63 DISC1 DTNBP1 ECPAS EMD GPX2 IL22RA2 IYD LATS1 LINC00839 LMNA MTDH MUSK MYOM1 NDEL1 NUP43 RAET1E RAET1L SH3BP5 TNIK TP53RK ULBP1 ULBP2 USP21 ZC3H12D
Entrez ID		112858	23345
HPRD ID		12276	09762
Ensembl ID		ENSG00000172315	ENSG00000131018
Uniprot IDs		Q96S44	A0A0C4DG40 B4E3R1 B7Z9Y6 F8WAI0 Q8NF91
PDB IDs		6WQX	4DXR 6R15 6XF2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?