PBX3 and ZNHIT3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PBX3	ZNHIT3
Description		PBX homeobox 3	zinc finger HIT-type containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nucleus Cytoplasm Pre-snoRNP Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Protein Binding Metal Ion Binding Thyroid Hormone Receptor Binding
	Biological Process	Eye Development Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Transcription By RNA Polymerase II Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Respiratory Gaseous Exchange By Respiratory System Adult Locomotory Behavior Animal Organ Morphogenesis Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Box C/D SnoRNP Assembly Regulation Of Transcription, DNA-templated SnoRNA Localization
Pathways
Drugs
Diseases
GWAS		Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Body mass index ( 26426971) Multiple sclerosis ( 31604244) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		64 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CIDEB CMTM4 CMTM5 CNTRL COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3	14 interacting genes: CSNK2A2 ESR2 FCMR HNF4A MBNL1 MEIS2 NUFIP1 PBX3 PITX2 PPARG RXRA THRB XRCC3 ZNF24
Entrez ID		5090	9326
HPRD ID		15938	05139
Ensembl ID		ENSG00000167081	ENSG00000273611
Uniprot IDs		P40426 Q5JS98 Q96AL5	A0A024R0X8 Q15649
PDB IDs			2YQQ 5L85
Enriched GO Terms of Interacting Partners?
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