PAX7 and HIRA

Number of citations of the paper that reports this interaction (PubMedID 9731536)
36

Data Source:
HPRD (two hybrid, in vitro)

		PAX7	HIRA
Description		paired box 7	histone cell cycle regulator
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	HIR Complex Chromatin Nucleus Nucleoplasm PML Body Protein-containing Complex Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding	Transcription Corepressor Activity Protein Binding Nucleosome Binding Histone Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Anatomical Structure Morphogenesis Negative Regulation Of Apoptotic Process Anatomical Structure Development	DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Negative Regulation Of Transcription, DNA-templated
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Body mass index ( 23669352) Cleft lip with or without cleft palate ( 28054174) Cortical surface area (visual PC2) ( 32198502) Knee osteoarthritis ( 28916551) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 33898419) Orofacial cleft x maternal periconceptional alcohol use interaction (2df) ( 33937227) Orofacial cleft x maternal periconceptional multivitamin use interaction (2df) ( 33937227) Orofacial cleft x maternal periconceptional smoking interaction (2df) ( 33937227) Orofacial clefts ( 22863734 28054174) Percentage gas trapping ( 26030696) Response to amphetamines ( 22952603) Urate levels in lean individuals ( 25811787)	Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		12 interacting genes: C1orf109 CIB1 CSNK2A1 CT55 FHL1 HIRA HOMER3 KRTAP19-7 MAGOHB NEDD4 SLC30A7 TCAP	16 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 TRIM55 TRIM63 UBE2I UPF1
Entrez ID		5081	7290
HPRD ID		01331	02583
Ensembl ID		ENSG00000009709	ENSG00000100084
Uniprot IDs		P23759	P54198
PDB IDs			2I32 5YJE
Enriched GO Terms of Interacting Partners?
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