HIRA and HIRIP3

Number of citations of the paper that reports this interaction (PubMedID 9710638)
36

Data Source:
HPRD (in vitro, in vivo)

		HIRA	HIRIP3
Description		histone cell cycle regulator	HIRA interacting protein 3
Image			No pdb structure
GO Annotations	Cellular Component	HIR Complex Chromatin Nucleus Nucleoplasm PML Body Protein-containing Complex Extracellular Exosome	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Transcription Corepressor Activity Protein Binding Nucleosome Binding Histone Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding
	Biological Process	DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Negative Regulation Of Transcription, DNA-templated	Chromatin Assembly Or Disassembly
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 25056061 29483656)
Interacting Genes		16 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 TRIM55 TRIM63 UBE2I UPF1	9 interacting genes: ABCF3 APP H2BC21 H3-4 H4C1 HIRA SGK2 SRPK1 SRPK2
Entrez ID		7290	8479
HPRD ID		02583	04531
Ensembl ID		ENSG00000100084	ENSG00000149929
Uniprot IDs		P54198	Q9BW71
PDB IDs		2I32 5YJE
Enriched GO Terms of Interacting Partners?
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