CLDN11 and ZP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLDN11	ZP3
Description		claudin 11	zona pellucida glycoprotein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Neurofilament Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Cell Junction Axon Basal Part Of Cell Tight Junction	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix Egg Coat Collagen-containing Extracellular Matrix
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Extracellular Matrix Structural Constituent Protein Binding Carbohydrate Binding Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding Receptor Ligand Activity
	Biological Process	Cell Adhesion Spermatogenesis Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly Tight Junction Assembly	Positive Regulation Of Type IV Hypersensitivity Blastocyst Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Leukocyte Migration Positive Regulation Of Humoral Immune Response Signal Transduction Binding Of Sperm To Zona Pellucida Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-4 Production Egg Coat Formation Positive Regulation Of T Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Oocyte Development Positive Regulation Of Inflammatory Response Positive Regulation Of Acrosome Reaction Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth
Pathways		Tight junction interactions	Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS		Blood glucose levels ( 31928498) Monocyte chemoattractant protein-1 (red blood cell fatty acid level interaction) ( 28820441) Prostate cancer ( 21743467)	Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		12 interacting genes: AMIGO1 C16orf54 FNDC9 KLRC1 SHISA3 SMIM3 SPINT1 TMEM80 TNFSF14 TSPAN3 TSPAN4 ZP3	11 interacting genes: ACR CLDN11 ENGASE FURIN MALL MICALL1 MRPS16 OR2L13 PCDH17 SPACA3 UBAP2L
Entrez ID		5010	7784
HPRD ID		03207	01690
Ensembl ID		ENSG00000013297	ENSG00000188372
Uniprot IDs		O75508	P21754
PDB IDs
Enriched GO Terms of Interacting Partners?
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