ZP3 and ENGASE

Number of citations of the paper that reports this interaction (PubMedID 8269854)
18

Data Source:
HPRD (in vitro)

		ZP3	ENGASE
Description		zona pellucida glycoprotein 3	endo-beta-N-acetylglucosaminidase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix Egg Coat Collagen-containing Extracellular Matrix	Cytosol
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Carbohydrate Binding Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding Receptor Ligand Activity	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Mannosyl-glycoprotein Endo-beta-N-acetylglucosaminidase Activity
	Biological Process	Positive Regulation Of Type IV Hypersensitivity Blastocyst Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Leukocyte Migration Positive Regulation Of Humoral Immune Response Signal Transduction Binding Of Sperm To Zona Pellucida Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-4 Production Egg Coat Formation Positive Regulation Of T Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Oocyte Development Positive Regulation Of Inflammatory Response Positive Regulation Of Acrosome Reaction Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth	Protein Folding Protein Deglycosylation
Pathways		Interaction With Cumulus Cells And The Zona Pellucida	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		11 interacting genes: ACR CLDN11 ENGASE FURIN MALL MICALL1 MRPS16 OR2L13 PCDH17 SPACA3 UBAP2L	1 interacting genes: ZP3
Entrez ID		7784	64772
HPRD ID		01690	10978
Ensembl ID		ENSG00000188372	ENSG00000167280
Uniprot IDs		P21754	Q8NFI3
PDB IDs
Enriched GO Terms of Interacting Partners?
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