ORM1 and GLUD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ORM1	GLUD1
Description		orosomucoid 1	glutamate dehydrogenase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Tertiary Granule Lumen	Cytoplasm Mitochondrion Mitochondrial Matrix Endoplasmic Reticulum
	Molecular Function	Protein Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Glutamate Dehydrogenase (NADP+) Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Regulation Of Immune System Process Acute-phase Response Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Tricarboxylic Acid Metabolic Process
Pathways		Platelet degranulation Neutrophil degranulation	Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs		Amsacrine Lidocaine Progesterone Chlorpromazine Dipyridamole Thalidomide	Glutamic acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride
Diseases
GWAS		End-stage coagulation ( 23381943) Thrombin generation potential phenotypes ( 24357727) Tourette syndrome ( 22889924)	Renal underexcretion gout ( 32238385)
Interacting Genes		9 interacting genes: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63	13 interacting genes: ASGR2 CRP CTNNB1 DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 OGT ORM1 STAT5A VTN
Entrez ID		5004	2746
HPRD ID		00724	11748
Ensembl ID		ENSG00000229314	ENSG00000148672
Uniprot IDs		P02763	E9KL48 P00367
PDB IDs		3KQ0	1L1F 1NR1 6DQG
Enriched GO Terms of Interacting Partners?
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