OAT and NUDT3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		OAT	NUDT3
Description		ornithine aminotransferase	nudix hydrolase 3
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm Cytosol
	Molecular Function	Ornithine-oxo-acid Transaminase Activity Protein Binding Pyridoxal Phosphate Binding Identical Protein Binding Ornithine(lysine) Transaminase Activity	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity
	Biological Process	Visual Perception Arginine Catabolic Process To Proline Via Ornithine Arginine Catabolic Process To Glutamate L-proline Biosynthetic Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process RNA Decapping Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways		Glutamate and glutamine metabolism	Synthesis of pyrophosphates in the cytosol
Drugs		Pyridoxal phosphate Ornithine Gabaculine Canaline
Diseases
GWAS			Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Body shape index ( 34021172) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Fasting insulin ( 34059833) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 34021172) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: FGFR2 NUDT3 OGT SLC35F6 TNFSF15 UBQLN4	36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		4942	11165
HPRD ID		02021	14849
Ensembl ID		ENSG00000065154	ENSG00000272325
Uniprot IDs		A0A140VJQ4 P04181	O95989
PDB IDs		1GBN 1OAT 2BYJ 2BYL 2CAN 2OAT 5VWO 6HX7 6OIA 6V8C 6V8D 7JX9	2FVV 2Q9P 6PCK 6PCL 6WO7 6WO8 6WO9 6WOA 6WOB 6WOC 6WOD 6WOE 6WOF 6WOG 6WOH 6WOI
Enriched GO Terms of Interacting Partners?
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