NUDT3 and WDR74

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		NUDT3	WDR74
Description		nudix hydrolase 3	WD repeat domain 74
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Preribosome, Large Subunit Precursor
	Molecular Function	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity	Protein Binding
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process RNA Decapping Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process	Blastocyst Formation RRNA Processing RNA Metabolic Process Ribosomal Large Subunit Biogenesis
Pathways		Synthesis of pyrophosphates in the cytosol
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Body shape index ( 34021172) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Fasting insulin ( 34059833) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 34021172) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	5 interacting genes: DLG4 NUDT3 RCHY1 RGS2 YIF1A
Entrez ID		11165	54663
HPRD ID		14849	08548
Ensembl ID		ENSG00000272325	ENSG00000133316
Uniprot IDs		O95989	Q6RFH5
PDB IDs		2FVV 2Q9P 6PCK 6PCL 6WO7 6WO8 6WO9 6WOA 6WOB 6WOC 6WOD 6WOE 6WOF 6WOG 6WOH 6WOI
Enriched GO Terms of Interacting Partners?
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