GPX8 and THBD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPX8	THBD
Description		glutathione peroxidase 8 (putative)	thrombomodulin
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Integral Component Of Membrane	Extracellular Space Vacuolar Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Apicolateral Plasma Membrane
	Molecular Function	Peroxidase Activity Glutathione Peroxidase Activity Protein Binding	Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding Signaling Receptor Activity
	Biological Process	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification	Female Pregnancy Blood Coagulation Response To X-ray Negative Regulation Of Platelet Activation Negative Regulation Of Blood Coagulation Response To Lipopolysaccharide Response To CAMP Negative Regulation Of Fibrinolysis
Pathways		Detoxification of Reactive Oxygen Species	Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs		Glutathione Glutathione disulfide	Drotrecogin alfa Ibuprofen Dexibuprofen
Diseases
GWAS		Cocaine dependence ( 31212010)	Blood protein levels in cardiovascular risk ( 28369058) Lung function (FVC) in asthma ( 32989782) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Venous thromboembolism ( 26888256)
Interacting Genes		152 interacting genes: - AGTRAP AIG1 ALG8 APOC3 APOD AQP1 AQP2 AQP3 ASGR1 ASPH BCL2L2 BET1 BIK BMP10 BNIP2 BTN2A2 C14orf180 C1GALT1 CACNG1 CD302 CD53 CD81 CDIPT CDS2 CFHR5 CHST1 CLDN19 CLEC1A CLEC2A CMTM5 CNIH1 CNIH3 COL4A5 COL8A2 CORIN CYB561 CYB561A3 CYB561D2 DNAJC30 DOLK EDDM3B ERG28 ERO1A FA2H FAM3C FAXDC2 GET3 GOSR2 GPR151 GPR37L1 GRINA GYPA HHATL HMOX2 IGFBP5 INSIG2 KIR2DL3 KLRG1 LAPTM4B LEPROTL1 LHFPL5 LNPEP LPAR3 MAN2B2 MARCHF2 MARCHF5 MFSD5 MFSD6 MGST2 MGST3 MIP MMD MYADML2 NEU1 NINJ1 NIPAL3 NKG7 NRM OCLN PAEP PAQR5 PAQR6 PGAP2 PLLP PLN PLP2 PLPP4 PLPP6 PNLIPRP1 PRB1 RBFA RND1 RTP2 SCARB2 SCARF1 SCD SEC22B SELENOK SERINC1 SERINC2 SERP1 SERTM1 SFTPC SGMS2 SLC13A3 SLC30A3 SLC34A3 SLC35A1 SLC35B4 SLC41A2 SMAGP SNORC ST6GAL2 STX3 STX8 SYT15 TF THBD TIMMDC1 TM4SF4 TMBIM6 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14B TMEM19 TMEM218 TMEM229B TMEM243 TMEM254 TMEM42 TMEM50B TMEM60 TMEM86B TMEM97 TMPRSS4 TMUB2 TRAM1L1 TSPAN33 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VKORC1L1 VSTM1 VTI1B YIF1A YIPF6 ZDHHC22	31 interacting genes: AIG1 APOC2 APOC4 AQP6 CD79A CIDEB CYBC1 EBP ERGIC3 F2 FAM209A FCER1G GPX8 KIR2DL3 LMNA MMGT1 MTIF3 MUC1 PDZK1IP1 PF4 PHF24 PROC PSENEN RHBDD2 SERPINA5 SLC19A3 SLC35C2 TMEM14B TMEM35A TMEM86B TMX2
Entrez ID		493869	7056
HPRD ID		17416	01764
Ensembl ID		ENSG00000164294	ENSG00000178726
Uniprot IDs		B4DPY0 E7ETY7 J3KNB5 Q8TED1	P07204
PDB IDs		3CYN 3KIJ	1ADX 1DQB 1DX5 1EGT 1FGD 1FGE 1HLT 1TMR 1ZAQ 2ADX 3GIS 5TO3
Enriched GO Terms of Interacting Partners?
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