NT5E and ATP6AP1

		NT5E	ATP6AP1
Description		5'-nucleotidase ecto	ATPase H+ transporting accessory protein 1
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Proton-transporting Two-sector ATPase Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Proton-transporting V-type ATPase, V1 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Binding 5'-nucleotidase Activity Metal Ion Binding	Protein Binding ATP Binding Small GTPase Binding
	Biological Process	AMP Catabolic Process DNA Metabolic Process Leukocyte Cell-cell Adhesion Dephosphorylation ADP Catabolic Process Adenosine Biosynthetic Process Negative Regulation Of Inflammatory Response	Cellular Iron Ion Homeostasis Regulation Of Cellular PH Cellular Response To Increased Oxygen Levels Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Bone Resorption PH Reduction Positive Regulation Of Exocytosis Establishment Of Organelle Localization Positive Regulation Of ERK1 And ERK2 Cascade Proton Transmembrane Transport Positive Regulation Of Osteoclast Development
Pathways		Nicotinate metabolism Pyrimidine catabolism Purine catabolism Purinergic signaling in leishmaniasis infection	Insulin receptor recycling RHOA GTPase cycle Transferrin endocytosis and recycling Ion channel transport
Drugs		Pentoxifylline	Tiludronic acid
Diseases
GWAS		Blood metabolite levels ( 24816252) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lung function ( 31902109) Metabolic traits ( 21886157) Serum metabolite levels ( 33031748)
Interacting Genes		7 interacting genes: ACTB AFF1 ATP6AP1 FN1 LAMA1 RNF24 ZNRF4	11 interacting genes: ABCD1 ANG CETN2 CTAG1B ERBB2 HBA1 LARP1 NR1I2 NT5E OGT RHOU
Entrez ID		4907	537
HPRD ID		00552	02184
Ensembl ID		ENSG00000135318	ENSG00000071553
Uniprot IDs		P21589 Q6NZX3	A0A0C4DGX8 A0A384MQW4 Q15904
PDB IDs		4H1S 4H1Y 4H2B 4H2F 4H2G 4H2I 6HXW 6S7F 6S7H 6TVE 6TVG 6TVX 6TW0 6TWA 6TWF 6XUE 6XUG 6XUQ 6YE1 6YE2 6Z9B 6Z9D 7JV8 7JV9	6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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