NOTCH4 and RBPJ

  • Number of citations of the paper that reports this interaction (PubMedID 11518718)
  • 52
  • Data Source:
  • HPRD (in vivo)

NOTCH4

RBPJ

Description notch receptor 4 recombination signal binding protein for immunoglobulin kappa J region
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced glycation end-product levels ( 26083729)
  • Age-related macular degeneration ( 22694956)
  • Aspartate aminotransferase levels ( 29403010)
  • Asthma ( 21804548 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Blood protein levels ( 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Body shape index ( 34021172)
  • Chronic hepatitis B infection ( 25802187)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
  • Colorectal cancer ( 30529582)
  • Crohn's disease ( 23266558)
  • Epstein-Barr virus immune response (EBNA-1) ( 23326239)
  • Food antigen IgG levels ( 24962563)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • High light scatter reticulocyte count ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • HIV-1 control ( 20041166)
  • Inflammatory bowel disease ( 28067908)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Joint mobility (Beighton score) ( 27182965)
  • Longevity ( 30294719)
  • Lung cancer ( 31577861 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Lupus nephritis in systemic lupus erythematosus ( 24925725)
  • Migraine ( 27322543)
  • Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430)
  • Obesity-related traits ( 23251661)
  • Objective response to lithium treatment in bipolar disorder ( 26503763)
  • Prostate cancer ( 23535732)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 27863252)
  • Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
  • Schizophrenia ( 19571808 30285260 23894747)
  • Squamous cell lung carcinoma ( 28604730)
  • Systemic lupus erythematosus ( 21408207 32771030)
  • Systemic sclerosis ( 21779181)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes (age at diagnosis) ( 33179336)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
  • Ulcerative colitis ( 24837172 28067908)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 22 interacting genes: DLL4 EGFL7 ELOC FBXW7 MAML1 MAML2 MAML3 MSH5 NEU1 NFKBIL1 NFYA PBX2 PSEN1 PSEN2 PSMB8 RBPJ SLC27A4 SMAD2 SMAD3 SMAD4 TDP2 WWP2 36 interacting genes: APP ART3 CCKAR CCNF CIR1 FHL1 GADD45A GSK3B HDAC1 HMGB1 HSPB1 INSL3 KAT2A KAT2B MAML1 MED27 NCOR1 NCOR2 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PTF1A RPS6KA6 RSC1A1 SEL1L3 SIN3A SND1 SNW1 SPEN SPOP SPTB SUFU TP53 ZCCHC4 ZDHHC7
Entrez ID 4855 3516
HPRD ID 01290 00920
Ensembl ID ENSG00000204301 ENSG00000168214
Uniprot IDs A0A1U9X983 Q99466 Q06330
PDB IDs 2F8X 3NBN 3V79 6PY8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?