NOS2 and RAC2

  • Number of citations of the paper that reports this interaction (PubMedID 11457725)
  • 23
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)
  • HPRD (two hybrid, in vivo, in vitro)

NOS2

RAC2

Description nitric oxide synthase 2 Rac family small GTPase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute anterior uveitis in ankylosing spondylitis ( 32492107)
  • Ankylosing spondylitis ( 23749187 30946743)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 23128233)
  • Cutaneous psoriasis ( 26626624)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • Inflammatory skin disease ( 25574825)
  • Psoriasis ( 25903422 20953189 23143594)
  • Psoriasis vulgaris ( 26626624)
  • Psoriatic arthritis ( 26626624)
Interacting Genes 14 interacting genes: AATF ACTB ACTN4 AP2B1 CAV1 CSF3 PEX5 RAC1 RAC2 SLC9A3R1 SPSB1 SPSB2 SPSB4 SRC 24 interacting genes: ACTB ADAM22 AFG3L2 AGAP2 ARFIP2 ARHGDIA ARHGDIB BRD2 CDC42 CHGB CHPF CUL1 DEF6 DOCK2 GDI1 HDAC7 ICMT NCF2 NOS2 NOXA1 PAK2 RTKN SMAD1 SMAD4
Entrez ID 4843 5880
HPRD ID 01225 03628
Ensembl ID ENSG00000007171 ENSG00000128340
Uniprot IDs P35228 A0A024R1P2 P15153 V9H0H7
PDB IDs 1NSI 2LL6 2NSI 3E7G 3EJ8 3HR4 4CX7 4NOS 5TP6 5XN3 6JWM 6JWN 6KEY 1DS6 2W2T 2W2V 2W2X
Enriched GO Terms of Interacting Partners?
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