NFKBIL1 and C2orf88

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NFKBIL1	C2orf88
Description		NFKB inhibitor like 1	chromosome 2 open reading frame 88
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Toll-like Receptor Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 23128233) Early chronic obstructive pulmonary disease in never smokers ( 33235445) Eosinophil counts ( 32888494) Glycated hemoglobin levels ( 34059833) Height ( 28552196) Hematocrit ( 32888494) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Neonatal lupus ( 20662065) Refractive error ( 32231278) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Sepsis (90-day mortality) ( 32592749) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Type 2 diabetes ( 30054458) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Daytime sleep phenotypes ( 27126917) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 34099189)
Interacting Genes		6 interacting genes: ADIPOR1 C2orf88 CASP10 CLEC18C NME7 NOTCH4	12 interacting genes: ARMC7 BATF2 CENPP FBXO7 MFSD6 MYOD1 NFKBIL1 PRKAR1A PRKAR2B RALGPS1 TDP2 ZMIZ2
Entrez ID		4795	84281
HPRD ID		07043	14436
Ensembl ID		ENSG00000204498	ENSG00000187699
Uniprot IDs		A0A0A0MRT5 A8K778 Q5STV6 Q9UBC1	Q9BSF0
PDB IDs			5HVZ
Enriched GO Terms of Interacting Partners?
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