NFKBIL1 and ADIPOR1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NFKBIL1	ADIPOR1
Description		NFKB inhibitor like 1	adiponectin receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Plasma Membrane Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity
	Biological Process	I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Toll-like Receptor Signaling Pathway Cellular Response To Lipopolysaccharide	Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Glucose Homeostasis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of NIK/NF-kappaB Signaling
Pathways			AMPK inhibits chREBP transcriptional activation activity AMPK inhibits chREBP transcriptional activation activity
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 23128233) Early chronic obstructive pulmonary disease in never smokers ( 33235445) Eosinophil counts ( 32888494) Glycated hemoglobin levels ( 34059833) Height ( 28552196) Hematocrit ( 32888494) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Neonatal lupus ( 20662065) Refractive error ( 32231278) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Sepsis (90-day mortality) ( 32592749) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Type 2 diabetes ( 30054458) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Mean platelet volume ( 32888494 27863252)
Interacting Genes		6 interacting genes: ADIPOR1 C2orf88 CASP10 CLEC18C NME7 NOTCH4	7 interacting genes: APPL1 CEP350 DPH3 NAA20 NFKBIL1 STK11 TBXA2R
Entrez ID		4795	51094
HPRD ID		07043	06402
Ensembl ID		ENSG00000204498	ENSG00000159346
Uniprot IDs		A0A0A0MRT5 A8K778 Q5STV6 Q9UBC1	Q96A54
PDB IDs			5LXG 6KRZ 6KS0
Enriched GO Terms of Interacting Partners?
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