NEK3 and NMNAT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NEK3	NMNAT1
Description		NIMA related kinase 3	nicotinamide nucleotide adenylyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Axon	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity	Nicotinamide-nucleotide Adenylyltransferase Activity Nicotinate-nucleotide Adenylyltransferase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Establishment Of Cell Polarity Neuron Projection Morphogenesis Cell Division Regulation Of Tubulin Deacetylation	Nucleotide Biosynthetic Process NAD Biosynthetic Process Response To Wounding Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Apoptotic DNA Fragmentation ATP Generation From Poly-ADP-D-ribose
Pathways			Nicotinate metabolism
Drugs		Fostamatinib	Nicotinamide Mononucleotide Deamido-Nad+
Diseases
GWAS			Resting heart rate ( 27798624)
Interacting Genes		6 interacting genes: BPGM CDCA8 NMNAT1 PRLR VAV1 VAV2	20 interacting genes: APP BANP CCNC FLOT2 GORASP2 KPNA1 KPNA2 KPNA3 KPNA5 KPNA6 MSX1 NEK3 NFATC2IP NTRK2 PABPC4 PICK1 RNF4 SIK1 SIRT1 TDO2
Entrez ID		4752	64802
HPRD ID		04954	16369
Ensembl ID		ENSG00000136098	ENSG00000173614
Uniprot IDs		P51956 Q6ZN64	A0A024R4E1 B1AN62 Q9HAN9
PDB IDs			1GZU 1KKU 1KQN 1KQO 1KR2
Enriched GO Terms of Interacting Partners?
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