NMNAT1 and KPNA5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NMNAT1	KPNA5
Description		nicotinamide nucleotide adenylyltransferase 1	karyopherin subunit alpha 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body	Nucleus Nucleoplasm Cytosol
	Molecular Function	Nicotinamide-nucleotide Adenylyltransferase Activity Nicotinate-nucleotide Adenylyltransferase Activity Protein Binding ATP Binding Identical Protein Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Nucleotide Biosynthetic Process NAD Biosynthetic Process Response To Wounding Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Apoptotic DNA Fragmentation ATP Generation From Poly-ADP-D-ribose	NLS-bearing Protein Import Into Nucleus
Pathways		Nicotinate metabolism	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs		Nicotinamide Mononucleotide Deamido-Nad+
Diseases
GWAS		Resting heart rate ( 27798624)	Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		20 interacting genes: APP BANP CCNC FLOT2 GORASP2 KPNA1 KPNA2 KPNA3 KPNA5 KPNA6 MSX1 NEK3 NFATC2IP NTRK2 PABPC4 PICK1 RNF4 SIK1 SIRT1 TDO2	28 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B DCPS EPAS1 FAM214B FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 NUP50 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326
Entrez ID		64802	3841
HPRD ID		16369	05179
Ensembl ID		ENSG00000173614	ENSG00000196911
Uniprot IDs		A0A024R4E1 B1AN62 Q9HAN9	O15131
PDB IDs		1GZU 1KKU 1KQN 1KQO 1KR2	4U2X
Enriched GO Terms of Interacting Partners?
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