NCK1 and EPHB1

  • Number of citations of the paper that reports this interaction (PubMedID 9430661)
  • 34
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (two hybrid)

NCK1

EPHB1

Description NCK adaptor protein 1 EPH receptor B1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199)
  • Blood urea nitrogen levels ( 31152163)
  • Body mass index ( 25673413)
  • Monocyte count ( 32888494)
  • Platelet count ( 32888494)
  • Platelet distribution width ( 32888494)
  • Schizophrenia ( 25056061 29483656)
  • Adult body size ( 32376654)
  • Bitter beverage consumption ( 31046077)
  • Body shape index ( 34021172)
  • CV-A6-associated hand, foot, and mouth disease (severe vs mild) ( 32634583)
  • Daytime sleep phenotypes ( 27126917)
  • Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
  • Familial lung adenocarcinoma ( 29924316)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Iron status biomarkers (total iron binding capacity) ( 28334935)
  • Mood instability ( 31168069)
  • Neurofibrillary tangles ( 31497858)
  • Small cell lung carcinoma ( 28604730)
  • Visceral adipose tissue adjusted for BMI ( 22589738)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip ratio ( 28552196)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 95 interacting genes: ABI1 ABI2 ABL1 ADAM15 ADGRL2 ARHGAP32 ARHGEF7 BCAR1 BLNK BRK1 CAV2 CBL CBLB CD3E CHN2 CRK CSNK1G2 CYFIP2 DAG1 DCC DLGAP4 DNM1 DOK1 DOK2 DRD3 DRD4 EFS EGFR EIF2B2 EIF2S2 EPHB1 EPHB2 ERBB2 ERBB3 ERBB4 FASLG FCHO1 FGFR1 FLT1 FLT3 FRS2 GAB1 GAB2 GMPPA HOMEZ KDR KHDRBS1 KIAA1522 KIT LCP2 MAP4K1 MAP4K4 MET MINK1 NCKAP1 NCKAP5 NCKIPSD NEDD9 NHSL2 NPHS1 NTRK2 NUTM2F OLIG1 PAK1 PAK2 PAK3 PDGFRB PFN1 PHC2 PIK3AP1 PIK3R3 PKN2 PLCG1 PTK2 PXN RAC1 RASA1 RHOU RRAS SH2D1A SHANK3 SOCS1 SOCS7 SORBS3 SOS1 SYNJ2 SYNPO TBK1 TNIK TNK2 UBA52 WAS WASF1 WASL WIPF1 23 interacting genes: AADAC ACP1 ACP3 AMOTL2 CTPS1 EFNA1 EFNA5 EFNB1 EFNB2 EPHB6 ERBB2 GM2A GRB10 GRB2 GTF2E1 MBD4 MRPL3 MTDH NCK1 PCCB PRKCG PXN UQCRC2
Entrez ID 4690 2047
HPRD ID 02740 02790
Ensembl ID ENSG00000158092 ENSG00000154928
Uniprot IDs A0A0S2Z4Y3 P16333 P54762
PDB IDs 2CI8 2CI9 2CUB 2JS0 2JS2 2JW4 5QU1 5QU2 5QU3 5QU4 5QU5 5QU6 5QU7 5QU8 5QUA 2DJS 2EAO 3ZFX 5MJA 5MJB 6UMW
Enriched GO Terms of Interacting Partners?
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