NCK1 and CHN2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

NCK1

CHN2

Description NCK adaptor protein 1 chimerin 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199)
  • Blood urea nitrogen levels ( 31152163)
  • Body mass index ( 25673413)
  • Monocyte count ( 32888494)
  • Platelet count ( 32888494)
  • Platelet distribution width ( 32888494)
  • Schizophrenia ( 25056061 29483656)
  • Circulating leptin levels in high cardiovascular risk ( 31766143)
  • CSF tryptophan concentration in tuberculous meningitis ( 29395996)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • Facial emotion recognition ( 28608620)
  • Facial emotion recognition (angry faces) ( 28608620)
  • Facial emotion recognition (sad faces) ( 28608620)
  • Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Loneliness (linear analysis) ( 27629369)
  • Methadone dose in opioid dependence ( 28115739)
  • Obesity-related traits ( 23251661)
  • Psychosis (atypical) ( 24132900)
  • Triglyceride levels ( 32203549)
  • Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes 95 interacting genes: ABI1 ABI2 ABL1 ADAM15 ADGRL2 ARHGAP32 ARHGEF7 BCAR1 BLNK BRK1 CAV2 CBL CBLB CD3E CHN2 CRK CSNK1G2 CYFIP2 DAG1 DCC DLGAP4 DNM1 DOK1 DOK2 DRD3 DRD4 EFS EGFR EIF2B2 EIF2S2 EPHB1 EPHB2 ERBB2 ERBB3 ERBB4 FASLG FCHO1 FGFR1 FLT1 FLT3 FRS2 GAB1 GAB2 GMPPA HOMEZ KDR KHDRBS1 KIAA1522 KIT LCP2 MAP4K1 MAP4K4 MET MINK1 NCKAP1 NCKAP5 NCKIPSD NEDD9 NHSL2 NPHS1 NTRK2 NUTM2F OLIG1 PAK1 PAK2 PAK3 PDGFRB PFN1 PHC2 PIK3AP1 PIK3R3 PKN2 PLCG1 PTK2 PXN RAC1 RASA1 RHOU RRAS SH2D1A SHANK3 SOCS1 SOCS7 SORBS3 SOS1 SYNJ2 SYNPO TBK1 TNIK TNK2 UBA52 WAS WASF1 WASL WIPF1 15 interacting genes: ANKK1 BAG6 ERBB3 ITGB8 NCK1 NCK2 RAC1 RACGAP1 RANBP3 RB1 SENP8 SHF SMARCD1 TGFBR1 TP53RK
Entrez ID 4690 1124
HPRD ID 02740 04173
Ensembl ID ENSG00000158092 ENSG00000106069
Uniprot IDs A0A0S2Z4Y3 P16333 A0A2X0TVW3 B3VCF4 B3VCF5 B3VCF6 B3VCF9 B7Z1V0 B7Z1W9 B7Z215 B7Z232 P52757
PDB IDs 2CI8 2CI9 2CUB 2JS0 2JS2 2JW4 5QU1 5QU2 5QU3 5QU4 5QU5 5QU6 5QU7 5QU8 5QUA 1XA6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?