PPP1R12A and ILF3

Number of citations of the paper that reports this interaction (PubMedID 31570000)
7

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		PPP1R12A	ILF3
Description		protein phosphatase 1 regulatory subunit 12A	interleukin enhancer binding factor 3
Image
GO Annotations	Cellular Component	Kinetochore Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc A Band Contractile Fiber PTW/PP1 Phosphatase Complex	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Phosphatase Regulator Activity Protein Kinase Binding 14-3-3 Protein Binding	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Mitotic Cell Cycle Protein Dephosphorylation Centrosome Cycle Signal Transduction Regulation Of Cell Adhesion Regulation Of Myosin-light-chain-phosphatase Activity Positive Regulation Of Myosin-light-chain-phosphatase Activity Negative Regulation Of Catalytic Activity Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleocytoplasmic Transport Cellular Response To Xenobiotic Stimulus Regulation Of Establishment Of Endothelial Barrier	Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways		Regulation of PLK1 Activity at G2/M Transition RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Platelet count ( 32888494) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Bipolar disorder ( 31043756) Chronotype ( 30696823) Height ( 25282103 25429064) Ischemic stroke ( 29531354) Obesity-related traits ( 23251661) Psoriasis ( 25903422 25574825 23143594) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 30423114) Stroke ( 29531354) Systemic lupus erythematosus ( 28714469)
Interacting Genes		14 interacting genes: ATXN10 CDKN3 DMPK IL16 ILF3 ILK KDM1A MPRIP PRKG1 RHOA ROCK1 ROCK2 SETD7 YWHAG	40 interacting genes: DHX9 DUX4 EIF2AK2 EP300 ERBB2 ERG ESR1 FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MAPK1 MDFI NDRG1 OGT PLSCR1 PPP1R12A PRMT1 PRMT5 PTEN RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC SPOP TRIM55 TRIM63 TRIP6 UBC VPS37C XAB2 XPO5 ZNF346 ZNF830
Entrez ID		4659	3609
HPRD ID		03606	04420
Ensembl ID		ENSG00000058272	ENSG00000129351
Uniprot IDs		B2RAH5 O14974	A0A024R7C7 Q12906
PDB IDs		2KJY 5HUZ	2L33 3P1X
Enriched GO Terms of Interacting Partners?
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