MYH3 and PRKD3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		MYH3	PRKD3
Description		myosin heavy chain 3	protein kinase D3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Sarcomere Myosin Filament Extracellular Exosome	Nucleoplasm Cytosol Membrane
	Molecular Function	Microfilament Motor Activity Calmodulin Binding ATP Binding ATP Hydrolysis Activity Myosin Phosphatase Activity Actin Filament Binding	Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Skeletal Muscle Contraction Protein Dephosphorylation Muscle Organ Development Actin Filament-based Movement Muscle Filament Sliding Embryonic Limb Morphogenesis Sarcomere Organization ATP Metabolic Process Face Morphogenesis	Protein Phosphorylation Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Sphingolipid Biosynthetic Process Protein Kinase D Signaling
Pathways		Striated Muscle Contraction	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Relative hand skill in reading disability ( 24068947)	Alzheimer's disease ( 34099642) Body mass index ( 28892062) Chronic lymphocytic leukemia ( 28165464 24292274) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Pulse pressure ( 27841878) Schizophrenia ( 33169155 23974872) Systolic blood pressure ( 28135244 27841878)
Interacting Genes		11 interacting genes: APPL1 CLIP4 DYSF GNG5 LAIR1 LAMTOR5 OPTN PPP1R7 PRKD3 SNAPIN TULP3	13 interacting genes: BCL6 DLAT DYNLL2 GSK3A IKBKG KPNA2 KPNB1 MYH3 NUDT3 POLL SKA2 TAF1 VAMP2
Entrez ID		4621	23683
HPRD ID		01172	06151
Ensembl ID		ENSG00000109063	ENSG00000115825
Uniprot IDs		P11055 Q5GJ67	O94806
PDB IDs			2D9Z
Enriched GO Terms of Interacting Partners?
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