MYBL2 and ZNF622

Number of citations of the paper that reports this interaction (PubMedID 12645566)
17

Data Source:
HPRD (in vivo, two hybrid)

		MYBL2	ZNF622
Description		MYB proto-oncogene like 2	zinc finger protein 622
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Myb Complex	Nucleoplasm Nucleolus Golgi Apparatus Cytosol Preribosome, Large Subunit Precursor
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Mitotic Spindle Assembly Cellular Response To Leukemia Inhibitory Factor	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Kinase Activity Ribosomal Large Subunit Biogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade
Pathways		Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Polo-like kinase mediated events TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS		Fasting insulin ( 34059833) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Attention function in attention deficit hyperactive disorder ( 26174813)
Interacting Genes		31 interacting genes: CCNA1 CCNA2 CCND1 CCNE1 CCNF CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN52 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBBP4 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622	9 interacting genes: APP BEND7 CDC42 HMGB2 MACROH2A1 MELK MYBL2 OGT PRKN
Entrez ID		4605	90441
HPRD ID		03247	12278
Ensembl ID		ENSG00000101057	ENSG00000173545
Uniprot IDs		P10244	Q969S3
PDB IDs		6C48	6LQM 6LSR
Enriched GO Terms of Interacting Partners?
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