MX2 and LSS

		MX2	LSS
Description		MX dynamin like GTPase 2	lanosterol synthase
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GO Annotations	Cellular Component	Nucleus Nuclear Pore Cytoplasm Cytosol Microtubule Membrane	Endoplasmic Reticulum Membrane Lipid Droplet Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding	Lanosterol Synthase Activity Protein Binding Beta-amyrin Synthase Activity
	Biological Process	Defense Response Response To Virus Protein Transport Response To Interferon-alpha Innate Immune Response Regulation Of Nucleocytoplasmic Transport MRNA Transport Defense Response To Virus Regulation Of Cell Cycle	Steroid Biosynthetic Process Cholesterol Biosynthetic Process Triterpenoid Biosynthetic Process Regulation Of Protein Stability
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs			R048-8071 Lanosterol
Diseases
GWAS		Cutaneous malignant melanoma ( 32341527) Melanoma ( 21983787 28212542) Nevus count or cutaneous melanoma ( 32341527 30429480) Parkinson disease and lewy body pathology ( 25663231) Tau burden ( 33426524)	White blood cell count ( 27863252)
Interacting Genes		9 interacting genes: ATRIP EHMT2 IGFBP4 LSS MX1 NDUFV3 PIAS2 PKNOX1 STK38L	12 interacting genes: AQP6 CIB1 GPR35 MX2 NR4A1 NUP214 SIRT5 SLC10A1 SLC10A6 TMEM167B TMEM86B YIF1A
Entrez ID		4600	4047
HPRD ID		01001	02945
Ensembl ID		ENSG00000183486	ENSG00000160285
Uniprot IDs		P20592	B2R694 P48449
PDB IDs		4WHJ 4X0R 5UOT	1W6J 1W6K
Enriched GO Terms of Interacting Partners?
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