MX1 and PSD3

Number of citations of the paper that reports this interaction (PubMedID 25447205)
6

Data Source:
BioGRID (two hybrid)

		MX1	PSD3
Description		MX dynamin like GTPase 1	pleckstrin and Sec7 domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Microtubule Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm	Postsynaptic Density Ruffle Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Apoptotic Process Defense Response Signal Transduction Response To Virus Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response	Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Body fat mass ( 28552196) Body mass index (change over time) in gastrointestinal cancer ( 28044437) Bone ultrasound measurement (velocity of sound) ( 28472463) Cognitive decline rate in late mild cognitive impairment ( 26252872) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery disease ( 33020668) Erythrocyte cadmium concentration in never smokers ( 27005419) Glucose homeostasis traits ( 30576415) HDL cholesterol levels in HIV infection ( 33109212) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Longitudinal cocaine use ( 31591132) Neutrophil count ( 21507922) Obesity-related traits ( 23251661) Paclitaxel-induced neuropathy ( 23776197) Perceived intensity of fructose ( 31005972) Schizophrenia ( 30285260) Serum metabolite levels ( 33031748) Sub-cortical grey matter volume ( 31530798) Survival in sporadic amyotrophic lateral sclerosis ( 27244217) Total cholesterol levels ( 33339817) Triglyceride levels ( 29403010 33339817 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Trunk fat mass ( 28552196) Urate levels in overweight individuals ( 25811787) Urinary albumin excretion rate in type 1 diabetes ( 24595857)
Interacting Genes		55 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CCL16 CD5 CHD3 DAXX DCP2 EPM2AIP1 FANCA FXR1 GGPS1 GMEB1 GPC4 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PIAS1 PIAS2 PLRG1 PRDX6 PSD3 PSG9 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZFP36 ZNF251 ZNF623	2 interacting genes: ARAP1 MX1
Entrez ID		4599	23362
HPRD ID		00919	11462
Ensembl ID		ENSG00000157601	ENSG00000156011
Uniprot IDs		P20591	B3KRC4 Q9NYI0
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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