MLLT1 and YIF1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MLLT1	YIF1A
Description		MLLT1 super elongation complex subunit	Yip1 interacting factor homolog A, membrane trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytosol Transcription Elongation Factor Complex	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288)	Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		14 interacting genes: AFF1 AFF4 ALKBH4 ARID1A BMI1 CBX8 FXR1 H1-5 H3-4 MLLT10 NFIX PAF1 WDR5 YIF1A	82 interacting genes: ADAM17 APOA5 AQP6 BNIP2 C4orf3 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GNL1 GPR37 GPR42 GPX8 HEATR1 JOSD2 KAT5 KCNK5 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MRPL18 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PRIM1 PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35C2 SLCO2B1 SNX10 SNX11 SNX2 STARD10 STIP1 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 WDR74 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27
Entrez ID		4298	10897
HPRD ID		15933	06755
Ensembl ID		ENSG00000130382	ENSG00000174851
Uniprot IDs		Q03111	A6NGW1 A8K509 O95070
PDB IDs		5J9S 6HPW 6HPX 6HPY 6HPZ 6HQ0 6HT0 6HT1 6T1I 6T1J 6T1L 6T1M 6T1N 6T1O 7B0T 7B10
Enriched GO Terms of Interacting Partners?
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