MAP3K4 and MAP2K6

  • Number of citations of the paper that reports this interaction (PubMedID 9841871)
  • 18
  • Data Source:
  • BioGRID (imaging technique)
  • HPRD (in vivo, in vitro)

MAP3K4

MAP2K6

Description mitogen-activated protein kinase kinase kinase 4 mitogen-activated protein kinase kinase 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aging ( 22773346)
  • Blood protein levels ( 28240269)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Lipoprotein (a) levels ( 26377243)
  • Ovarian disease with few adhesions ( 28333195)
  • Body shape index ( 34021172)
  • Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
  • Eye color ( 33692100)
  • Optic disc size ( 31809533)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
  • Waist-hip ratio ( 28552196)
Interacting Genes 27 interacting genes: ANXA2 AXIN1 BUB1B CDC42 CHUK CNTRL DIXDC1 EPHB4 GADD45A GADD45B GADD45G GSK3B MAP2K1 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPK13 MFHAS1 PTK2B PTPN11 RAC1 RACGAP1 RUNX2 TPR TRAF4 YWHAZ 39 interacting genes: AKT1 BECN1 BRAF CCND2 CDKN2B DCTN1 EPHA2 FBXO7 FGFR4 GLIS2 HGF HRAS LRRK2 MAP2K3 MAP2K4 MAP2K5 MAP3K20 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 NFE2L2 PICK1 PKN1 PLCB2 RAF1 RASSF1 RELA SMAD7 STAT4 STK11 TAOK2 TLR3 TRAF6
Entrez ID 4216 5608
HPRD ID 03886 03155
Ensembl ID ENSG00000085511 ENSG00000108984
Uniprot IDs Q9P1M2 Q9Y6R4 A0A024R8K3 A8K3Y2 P52564
PDB IDs 2Y8O 3ENM 3FME 3VN9 5ETF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?