MCM2 and CDC45

  • Number of citations of the paper that reports this interaction (PubMedID 22374673)
  • 12
  • Data Source:
  • BioGRID (fluorescent resonance energy transfer, affinity chromatography technology)

MCM2

CDC45

Description minichromosome maintenance complex component 2 cell division cycle 45
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Red cell distribution width ( 32888494)
  • Refractive error ( 32231278)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes 58 interacting genes: AKAP8 APP ASF1A ATM ATR CCNB2 CCNC CD86 CDC45 CDC6 CDC7 CDK2 CDK4 CDK6 CDKN2A CDT1 CPSF1 CSNK2A1 DBF4 ELL EP300 ESCO2 FBXO7 GINS4 GNB5 GTF2B GTF2H1 H3-4 KAT7 MCM10 MCM3 MCM4 MCM5 MCM6 MCM7 MCPH1 MOB4 MPP3 ORC1 ORC2 ORC4 ORC5 ORC6 P2RX4 PHB PHC2 PLK1 PTEN RAD52 RPA1 RPA2 RPA3 RPS4X SIK1 TBP TCEA2 TERF1 TERF2IP 25 interacting genes: CAMK1G CDK4 CDKN1A CDKN2A CEP55 CSK GINS4 LCK MAPK3 MCM10 MCM2 MCM3 MCM6 MCM7 ORC1 ORC2 ORC3 ORC5 ORC6 POLA1 RAB4B TOPBP1 TRAPPC3 UBC ZRANB1
Entrez ID 4171 8318
HPRD ID 00303 09145
Ensembl ID ENSG00000073111 ENSG00000093009
Uniprot IDs P49736 O75419
PDB IDs 4UUZ 5BNV 5BNX 5BO0 5C3I 5JA4 6XTX 6XTY 6YA7 5DGO 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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