MCF2 and ERCC3

Number of citations of the paper that reports this interaction (PubMedID 10403766)
2

Data Source:
BioGRID (pull down)

		MCF2	ERCC3
Description		MCF.2 cell line derived transforming sequence	ERCC excision repair 3, TFIIH core complex helicase subunit
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Membrane	Nucleotide-excision Repair Factor 3 Complex Transcription Factor TFIIH Core Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIH Holo Complex Transcription Preinitiation Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	DNA Binding Damaged DNA Binding Protein Binding ATP Binding Protein C-terminus Binding ATP Hydrolysis Activity 3'-5' DNA Helicase Activity Protein N-terminus Binding Promoter-specific Chromatin Binding
	Biological Process	Dendrite Development Intracellular Signal Transduction Negative Regulation Of Axonogenesis Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Leukemia Inhibitory Factor	Nucleotide-excision Repair, DNA Duplex Unwinding Response To Hypoxia DNA Topological Change DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription Elongation From RNA Polymerase I Promoter Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Apoptotic Process Response To Oxidative Stress Protein Localization Response To UV UV Protection Nucleotide-excision Repair, DNA Incision Hair Cell Differentiation Positive Regulation Of Apoptotic Process Embryonic Organ Development Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Axonal growth inhibition (RHOA activation) NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Tat-mediated elongation of the HIV-1 transcript NoRC negatively regulates rRNA expression Formation of Incision Complex in GG-NER Dual Incision in GG-NER RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes mRNA Capping RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Transcription Termination RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		9 interacting genes: ERCC3 GNA13 GNB1 RAC1 RHOA RHOG SHANK2 STUB1 TNK2	37 interacting genes: ADAMTSL4 AR BCR BLZF1 CCNC CCNH CDC42 CDK7 CDK8 CEP70 CEP76 E2F1 ERCC2 GOLGA2 GTF2E1 GTF2E2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KPNA3 MAGED1 MCF2 MNAT1 MSANTD2 PSMC5 RAD52 ROPN1 SNW1 SRPK2 TP53 TRIM14 TRIM27 XIAP XPC ZSCAN1
Entrez ID		4168	2071
HPRD ID		02406	00593
Ensembl ID		ENSG00000101977	ENSG00000163161
Uniprot IDs		B2R9S6 P10911	B3KRG2 B3KTH1 G3V1S1 P19447
PDB IDs			4ERN 5IVW 5IY6 5IY7 5IY8 5IY9 5OF4 6NMI 6O9L 6O9M 6RO4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?