AASS and PTPRZ1

		AASS	PTPRZ1
Description		aminoadipate-semialdehyde synthase	protein tyrosine phosphatase receptor type Z1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane Synapse Perineuronal Net
	Molecular Function	Transcription Corepressor Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Histone Binding Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process Lysine Biosynthetic Process Via Aminoadipic Acid Negative Regulation Of Histone Methylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine	Hematopoietic Progenitor Cell Differentiation Protein Dephosphorylation Axonogenesis Central Nervous System Development Learning Or Memory Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation
Pathways		Lysine catabolism	Signaling by ALK Other interleukin signaling
Drugs		Glutamic acid NADH NADPH L-Saccharopine
Diseases
GWAS		Opioid dependence (time to event) ( 34124712)	Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)
Interacting Genes		7 interacting genes: ARF5 CCR6 CHCHD3 FSCN3 OGT PTPRZ1 WASL	16 interacting genes: AASS ADD2 ALK ARHGAP35 BMP1 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B NMB PTN PTPRF TNR
Entrez ID		10157	5803
HPRD ID		05489	01481
Ensembl ID		ENSG00000008311	ENSG00000106278
Uniprot IDs		A4D0W4 Q9UDR5	B4DFE7 P23471
PDB IDs		5L76 5L78 5O1N 5O1O 5O1P	3JXF 3S97 5AWX 5H08
Enriched GO Terms of Interacting Partners?
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