KIF2A and KLC1

Number of citations of the paper that reports this interaction (PubMedID 17332754)
63

Data Source:
HPRD (in vivo)

		KIF2A	KLC1
Description		kinesin family member 2A	kinesin light chain 1
Image
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Spindle Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Body Centriolar Subdistal Appendage	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle
	Molecular Function	Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity	Cytoskeletal Motor Activity Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule-based Movement Microtubule Depolymerization Mitotic Spindle Organization Nervous System Development Cell Differentiation Regulation Of Cell Migration Cell Division Mitotic Spindle Assembly	Stress Granule Disassembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Signaling by ALK fusions and activated point mutants Kinesins
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		13 interacting genes: CASK CLSTN1 DYNLT1 FAM13C FXR2 H3-4 KLC1 KLC2 LARP1B LMO2 LMO3 MRPL53 SUMO2	33 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CDC42BPB CLSTN1 ERBB2 F2RL1 GPR132 HSPB1 JAG2 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 POLR1E PTGER4 SNCA SPAG9 TACC3 TSC1 YWHAB
Entrez ID		3796	3831
HPRD ID		03996	02489
Ensembl ID		ENSG00000068796	ENSG00000126214
Uniprot IDs		A0A6Q8PFA6 B0AZS5 O00139	Q07866 Q7RTQ2
PDB IDs		2GRY 6BBN	3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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