KLC1 and KLC2

Number of citations of the paper that reports this interaction (PubMedID 26496610)
430

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		KLC1	KLC2
Description		kinesin light chain 1	kinesin light chain 2
Image
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle	Nucleoplasm Mitochondrion Lysosomal Membrane Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	Cytoskeletal Motor Activity Protein Binding	Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Stress Granule Disassembly	Lysosome Localization
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Signaling by ALK fusions and activated point mutants Kinesins	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		33 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CDC42BPB CLSTN1 ERBB2 F2RL1 GPR132 HSPB1 JAG2 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 POLR1E PTGER4 SNCA SPAG9 TACC3 TSC1 YWHAB	18 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 DYNC1I1 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PACS1 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ
Entrez ID		3831	64837
HPRD ID		02489	13917
Ensembl ID		ENSG00000126214	ENSG00000174996
Uniprot IDs		Q07866 Q7RTQ2	Q9H0B6
PDB IDs		3NF1 5OJ8	3CEQ 3EDT
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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